Fasting-induced JMJD3 histone demethylase epigenetically activates mitochondrial fatty acid β-oxidation

Jumonji D3 (JMJD3) histone demethylase epigenetically regulates development and differentiation, immunity, and tumorigenesis by demethylating a gene repression histone mark, H3K27-me3, but a role for JMJD3 in metabolic regulation has not been described. SIRT1 deacetylase maintains energy balance dur...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Seok, Sunmi, Kim, Young-Chae, Byun, Sangwon, Choi, Sunge, Xiao, Zhen, Iwamori, Naoki, Zhang, Yang, Wang, Chaochen, Ma, Jian, Ge, Kai, Kemper, Byron, Kemper, Jongsook Kim
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6025975/
https://ncbi.nlm.nih.gov/pubmed/29911994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI97736
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