A carregar...
A Context-Dependent Role for the RNF146 Ubiquitin Ligase in Wingless/Wnt Signaling in Drosophila
Aberrant activation of the Wnt signal transduction pathway triggers the development of colorectal cancer. The ADP-ribose polymerase Tankyrase (TNKS) mediates proteolysis of Axin—a negative regulator of Wnt signaling—and provides a promising therapeutic target for Wnt-driven diseases. Proteolysis of...
Na minha lista:
| Publicado no: | Genetics |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Genetics Society of America
2019
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6404254/ https://ncbi.nlm.nih.gov/pubmed/30593492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.118.301393 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|