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Toggling a Conformational Switch in Wnt/β-catenin Signaling: Regulation of Axin Phosphorylation
The precise orchestration of two opposing protein complexes - one in the cytoplasm (β-catenin destruction complex) and the other at the plasma membrane (LRP6 signaling complex) – is critical for controlling levels of the transcriptional co-factor, β-catenin, and subsequent activation of the Wnt/β-ca...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3878292/ https://ncbi.nlm.nih.gov/pubmed/24105937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201300101 |
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