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Dual Roles for Membrane Association of Drosophila Axin in Wnt Signaling
Deregulation of the Wnt signal transduction pathway underlies numerous congenital disorders and cancers. Axin, a concentration-limiting scaffold protein, facilitates assembly of a “destruction complex” that prevents signaling in the unstimulated state and a plasma membrane-associated “signalosome” t...
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| Publicado no: | PLoS Genet |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5154497/ https://ncbi.nlm.nih.gov/pubmed/27959917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006494 |
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