Protease-Activatable Adeno-Associated Virus Vector for Gene Delivery to Damaged Heart Tissue

Adeno-associated virus (AAV) has emerged as a promising gene delivery vector because of its non-pathogenicity, simple structure and genome, and low immunogenicity compared to other viruses. However, its adoption as a safe and effective delivery vector for certain diseases relies on altering its trop...

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Bibliografski detalji
Izdano u:Mol Ther
Glavni autori: Guenther, Caitlin M., Brun, Mitchell J., Bennett, Antonette D., Ho, Michelle L., Chen, Weitong, Zhu, Banghe, Lam, Michael, Yamagami, Momona, Kwon, Sunkuk, Bhattacharya, Nilakshee, Sousa, Duncan, Evans, Annicka C., Voss, Julie, Sevick-Muraca, Eva M., Agbandje-McKenna, Mavis, Suh, Junghae
Format: Artigo
Jezik:Inglês
Izdano: American Society of Gene & Cell Therapy 2019
Teme:
Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6404099/
https://ncbi.nlm.nih.gov/pubmed/30772143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.01.015
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