Protease-Activatable Adeno-Associated Virus Vector for Gene Delivery to Damaged Heart Tissue

Adeno-associated virus (AAV) has emerged as a promising gene delivery vector because of its non-pathogenicity, simple structure and genome, and low immunogenicity compared to other viruses. However, its adoption as a safe and effective delivery vector for certain diseases relies on altering its trop...

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Foilsithe in:Mol Ther
Main Authors: Guenther, Caitlin M., Brun, Mitchell J., Bennett, Antonette D., Ho, Michelle L., Chen, Weitong, Zhu, Banghe, Lam, Michael, Yamagami, Momona, Kwon, Sunkuk, Bhattacharya, Nilakshee, Sousa, Duncan, Evans, Annicka C., Voss, Julie, Sevick-Muraca, Eva M., Agbandje-McKenna, Mavis, Suh, Junghae
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society of Gene & Cell Therapy 2019
Ábhair:
Original Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6404099/
https://ncbi.nlm.nih.gov/pubmed/30772143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.01.015
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