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Adeno-associated virus structural biology as a tool in vector development

Adeno-associated viruses (AAVs) have become important therapeutic gene delivery vectors in recent years. However, there are challenges, including intractable tissues/cell types and pre-existing immune responses, which need to be overcome for full realization of this system. This review addresses str...

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Detalhes bibliográficos
Main Authors: Drouin, Lauren M, Agbandje-McKenna, Mavis
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3921901/
https://ncbi.nlm.nih.gov/pubmed/24533032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fvl.13.112
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