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Protease-Activatable Adeno-Associated Virus Vector for Gene Delivery to Damaged Heart Tissue

Adeno-associated virus (AAV) has emerged as a promising gene delivery vector because of its non-pathogenicity, simple structure and genome, and low immunogenicity compared to other viruses. However, its adoption as a safe and effective delivery vector for certain diseases relies on altering its trop...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Guenther, Caitlin M., Brun, Mitchell J., Bennett, Antonette D., Ho, Michelle L., Chen, Weitong, Zhu, Banghe, Lam, Michael, Yamagami, Momona, Kwon, Sunkuk, Bhattacharya, Nilakshee, Sousa, Duncan, Evans, Annicka C., Voss, Julie, Sevick-Muraca, Eva M., Agbandje-McKenna, Mavis, Suh, Junghae
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6404099/
https://ncbi.nlm.nih.gov/pubmed/30772143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.01.015
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