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Constructing and Evaluating Caspase-Activatable Adeno-Associated Virus Vector for Gene Delivery to Injured Heart
Adeno-associated virus (AAV) is a promising vector for gene therapy, but its broad tropism can be detrimental if the transgene being delivered is harmful when expressed ubiquitously in the body, i.e. in non-target tissues. Delivering the transgene of interest to target cells at levels high enough to...
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| Publicado no: | J Control Release |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7770761/ https://ncbi.nlm.nih.gov/pubmed/33157191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2020.10.058 |
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