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Adeno-Associated Virus (AAV) Vectors: Rational Design Strategies for Capsid Engineering

Adeno-associated virus (AAV) consists of a simple genome, infects mammalian cells, displays nonpathogenicity in humans, and spans an array of serotypes and variants bearing distinct tissue tropisms. These attributes lend AAV tremendous promise as a gene delivery vector, further substantiated by its...

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書目詳細資料
發表在:Curr Opin Biomed Eng
Main Authors: Lee, Esther J., Guenther, Caitlin M., Suh, Junghae
格式: Artigo
語言:Inglês
出版: 2018
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6516759/
https://ncbi.nlm.nih.gov/pubmed/31106283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cobme.2018.09.004
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