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Site-Specific Post-translational Surface Modification of Adeno-Associated Virus Vectors Using Leucine Zippers

Adeno-associated virus (AAV) is widely favored as a gene therapy vector, tested in over 200 clinical trials internationally. To improve targeted delivery a variety of genetic capsid modifications, such as insertion of targeting proteins/peptides into the capsid shell, have been explored with some su...

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Podrobná bibliografie
Vydáno v:ACS Synth Biol
Hlavní autoři: Thadani, Nicole N., Yang, Joanna, Moyo, Buhle, Lee, Ciaran M., Chen, Maria Y., Bao, Gang, Suh, Junghae
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7323921/
https://ncbi.nlm.nih.gov/pubmed/32068391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssynbio.9b00341
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