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Site-Specific Post-translational Surface Modification of Adeno-Associated Virus Vectors Using Leucine Zippers
Adeno-associated virus (AAV) is widely favored as a gene therapy vector, tested in over 200 clinical trials internationally. To improve targeted delivery a variety of genetic capsid modifications, such as insertion of targeting proteins/peptides into the capsid shell, have been explored with some su...
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| Publicado no: | ACS Synth Biol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7323921/ https://ncbi.nlm.nih.gov/pubmed/32068391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssynbio.9b00341 |
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