HIV Subtype and Nef-Mediated Immune Evasion Function Correlate with Viral Reservoir Size in Early-Treated Individuals

The HIV accessory protein Nef modulates key immune evasion and pathogenic functions, and its encoding gene region exhibits high sequence diversity. Given the recent identification of early HIV-specific adaptive immune responses as novel correlates of HIV reservoir size, we hypothesized that viral fa...

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Bibliografiset tiedot
Julkaisussa:J Virol
Päätekijät: Omondi, Fredrick H., Chandrarathna, Sandali, Mujib, Shariq, Brumme, Chanson J., Jin, Steven W., Sudderuddin, Hanwei, Miller, Rachel L., Rahimi, Asa, Laeyendecker, Oliver, Bonner, Phil, Yue, Feng Yun, Benko, Erika, Kovacs, Colin M., Brockman, Mark A., Ostrowski, Mario, Brumme, Zabrina L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2019
Aiheet:
Pathogenesis and Immunity
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401425/
https://ncbi.nlm.nih.gov/pubmed/30602611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01832-18
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