HIV Subtype and Nef-Mediated Immune Evasion Function Correlate with Viral Reservoir Size in Early-Treated Individuals

The HIV accessory protein Nef modulates key immune evasion and pathogenic functions, and its encoding gene region exhibits high sequence diversity. Given the recent identification of early HIV-specific adaptive immune responses as novel correlates of HIV reservoir size, we hypothesized that viral fa...

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發表在:J Virol
Main Authors: Omondi, Fredrick H., Chandrarathna, Sandali, Mujib, Shariq, Brumme, Chanson J., Jin, Steven W., Sudderuddin, Hanwei, Miller, Rachel L., Rahimi, Asa, Laeyendecker, Oliver, Bonner, Phil, Yue, Feng Yun, Benko, Erika, Kovacs, Colin M., Brockman, Mark A., Ostrowski, Mario, Brumme, Zabrina L.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2019
主題:
Pathogenesis and Immunity
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401425/
https://ncbi.nlm.nih.gov/pubmed/30602611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01832-18
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