HIV Subtype and Nef-Mediated Immune Evasion Function Correlate with Viral Reservoir Size in Early-Treated Individuals

The HIV accessory protein Nef modulates key immune evasion and pathogenic functions, and its encoding gene region exhibits high sequence diversity. Given the recent identification of early HIV-specific adaptive immune responses as novel correlates of HIV reservoir size, we hypothesized that viral fa...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Omondi, Fredrick H., Chandrarathna, Sandali, Mujib, Shariq, Brumme, Chanson J., Jin, Steven W., Sudderuddin, Hanwei, Miller, Rachel L., Rahimi, Asa, Laeyendecker, Oliver, Bonner, Phil, Yue, Feng Yun, Benko, Erika, Kovacs, Colin M., Brockman, Mark A., Ostrowski, Mario, Brumme, Zabrina L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401425/
https://ncbi.nlm.nih.gov/pubmed/30602611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01832-18
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