HIV Subtype and Nef-Mediated Immune Evasion Function Correlate with Viral Reservoir Size in Early-Treated Individuals

The HIV accessory protein Nef modulates key immune evasion and pathogenic functions, and its encoding gene region exhibits high sequence diversity. Given the recent identification of early HIV-specific adaptive immune responses as novel correlates of HIV reservoir size, we hypothesized that viral fa...

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Vydáno v:J Virol
Hlavní autoři: Omondi, Fredrick H., Chandrarathna, Sandali, Mujib, Shariq, Brumme, Chanson J., Jin, Steven W., Sudderuddin, Hanwei, Miller, Rachel L., Rahimi, Asa, Laeyendecker, Oliver, Bonner, Phil, Yue, Feng Yun, Benko, Erika, Kovacs, Colin M., Brockman, Mark A., Ostrowski, Mario, Brumme, Zabrina L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2019
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401425/
https://ncbi.nlm.nih.gov/pubmed/30602611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01832-18
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