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Ectopic lipid deposition mediates insulin resistance in adipose specific 11β-Hydroxysteroid Dehydrogenase type 1 transgenic mice

CONTEXT: Excessive adipose glucocorticoid action is associated with insulin resistance, but the mechanisms linking adipose glucocorticoid action to insulin resistance are still debated. We hypothesized that insulin resistance from excess glucocorticoid action may be attributed in part to increased e...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Metabolism
Hauptverfasser: Abulizi, Abudukadier, Camporez, João-Paulo, Zhang, Dongyan, Samuel, Varman T., Shulman, Gerald I., Vatner, Daniel F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401251/
https://ncbi.nlm.nih.gov/pubmed/30576689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2018.12.003
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