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Insulin and Dexamethasone Dynamically Regulate Adipocyte 11β-Hydroxysteroid Dehydrogenase Type 1

The adipocyte enzyme 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) amplifies local glucocorticoid action by generating active glucocorticoids from inactive metabolites and has emerged as a key player in the pathogenesis of central obesity and metabolic syndrome. However, the regulation of adipo...

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Autores principales: Balachandran, Aran, Guan, Haiyan, Sellan, Michael, van Uum, Stan, Yang, Kaiping
Formato: Artigo
Lenguaje:Inglês
Publicado: The Endocrine Society 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2488250/
https://ncbi.nlm.nih.gov/pubmed/18467433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-0088
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