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Caffeine Reduces 11β-Hydroxysteroid Dehydrogenase Type 2 Expression in Human Trophoblast Cells through the Adenosine A(2B) Receptor

Maternal caffeine consumption is associated with reduced fetal growth, but the underlying molecular mechanisms are unknown. Since there is evidence that decreased placental 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) is linked to fetal growth restriction, we hypothesized that caffeine may inh...

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Detalhes bibliográficos
Main Authors: Sharmin, Saina, Guan, Haiyan, Williams, Andrew Scott, Yang, Kaiping
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372487/
https://ncbi.nlm.nih.gov/pubmed/22701600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038082
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