Elevated hepatic 11β-hydroxysteroid dehydrogenase type 1 induces insulin resistance in uremia

Insulin resistance and associated metabolic sequelae are common in chronic kidney disease (CKD) and are positively and independently associated with increased cardiovascular mortality. However, the pathogenesis has yet to be fully elucidated. 11β-Hydroxysteroid dehydrogenase type 1 (11βHSD1) catalyz...

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Detalhes bibliográficos
Main Authors: Chapagain, Ananda, Caton, Paul W., Kieswich, Julius, Andrikopoulos, Petros, Nayuni, Nanda, Long, Jamie H., Harwood, Steven M., Webster, Scott P., Raftery, Martin J., Thiemermann, Christoph, Walker, Brian R., Seckl, Jonathan R., Corder, Roger, Yaqoob, Muhammad Magdi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3956172/
https://ncbi.nlm.nih.gov/pubmed/24569863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1312436111
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