Elevated hepatic 11β-hydroxysteroid dehydrogenase type 1 induces insulin resistance in uremia

Insulin resistance and associated metabolic sequelae are common in chronic kidney disease (CKD) and are positively and independently associated with increased cardiovascular mortality. However, the pathogenesis has yet to be fully elucidated. 11β-Hydroxysteroid dehydrogenase type 1 (11βHSD1) catalyz...

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מידע ביבליוגרפי
Main Authors: Chapagain, Ananda, Caton, Paul W., Kieswich, Julius, Andrikopoulos, Petros, Nayuni, Nanda, Long, Jamie H., Harwood, Steven M., Webster, Scott P., Raftery, Martin J., Thiemermann, Christoph, Walker, Brian R., Seckl, Jonathan R., Corder, Roger, Yaqoob, Muhammad Magdi
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2014
נושאים:
Biological Sciences
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3956172/
https://ncbi.nlm.nih.gov/pubmed/24569863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1312436111
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