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Multi-color lineage tracing reveals clonal dynamics of squamous carcinoma evolution from initiation to metastasis
Tumor cells are subjected to evolutionary selection pressures during progression from initiation to metastasis. We analyzed the clonal evolution of squamous skin carcinomas induced by DMBA/TPA treatment using the K5CreER-Confetti mouse and stage-specific lineage tracing. We show that benign tumors a...
Gorde:
| Argitaratua izan da: | Nat Cell Biol |
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| Egile Nagusiak: | , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2018
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6400587/ https://ncbi.nlm.nih.gov/pubmed/29802408 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-018-0109-0 |
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