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Multi-color lineage tracing reveals clonal dynamics of squamous carcinoma evolution from initiation to metastasis
Tumor cells are subjected to evolutionary selection pressures during progression from initiation to metastasis. We analyzed the clonal evolution of squamous skin carcinomas induced by DMBA/TPA treatment using the K5CreER-Confetti mouse and stage-specific lineage tracing. We show that benign tumors a...
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| Publicado no: | Nat Cell Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6400587/ https://ncbi.nlm.nih.gov/pubmed/29802408 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-018-0109-0 |
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