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Multicolor lineage tracing reveals clonal architecture and dynamics in colon cancer
Colon cancers are composed of phenotypically heterogeneous tumor cell subpopulations with variable expression of putative stem cell and differentiation antigens. While in normal colonic mucosa, clonal repopulation occurs along differentiation gradients from crypt base toward crypt apex, the clonal a...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5681634/ https://ncbi.nlm.nih.gov/pubmed/29127276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00976-9 |
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