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Single-cell lineage tracing in the mammary gland reveals stochastic clonal dispersion of stem/progenitor cell progeny

The mammary gland undergoes cycles of growth and regeneration throughout reproductive life, a process that requires mammary stem cells (MaSCs). Whilst recent genetic fate-mapping studies using lineage-specific promoters have provided valuable insights into the mammary epithelial hierarchy, the true...

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Vydáno v:Nat Commun
Hlavní autoři: Davis, Felicity M., Lloyd-Lewis, Bethan, Harris, Olivia B., Kozar, Sarah, Winton, Douglas J., Muresan, Leila, Watson, Christine J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5093309/
https://ncbi.nlm.nih.gov/pubmed/27779190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13053
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