A major role for ferroptosis in Mycobacterium tuberculosis–induced cell death and tissue necrosis

Necrotic cell death during Mycobacterium tuberculosis (Mtb) infection is considered host detrimental since it facilitates mycobacterial spread. Ferroptosis is a type of regulated necrosis induced by accumulation of free iron and toxic lipid peroxides. We observed that Mtb-induced macrophage necrosis...

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Dades bibliogràfiques
Publicat a:J Exp Med
Autors principals: Amaral, Eduardo P., Costa, Diego L., Namasivayam, Sivaranjani, Riteau, Nicolas, Kamenyeva, Olena, Mittereder, Lara, Mayer-Barber, Katrin D., Andrade, Bruno B., Sher, Alan
Format: Artigo
Idioma:Inglês
Publicat: Rockefeller University Press 2019
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400546/
https://ncbi.nlm.nih.gov/pubmed/30787033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20181776
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