A major role for ferroptosis in Mycobacterium tuberculosis–induced cell death and tissue necrosis

Necrotic cell death during Mycobacterium tuberculosis (Mtb) infection is considered host detrimental since it facilitates mycobacterial spread. Ferroptosis is a type of regulated necrosis induced by accumulation of free iron and toxic lipid peroxides. We observed that Mtb-induced macrophage necrosis...

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Detalhes bibliográficos
Publicado no:J Exp Med
Principais autores: Amaral, Eduardo P., Costa, Diego L., Namasivayam, Sivaranjani, Riteau, Nicolas, Kamenyeva, Olena, Mittereder, Lara, Mayer-Barber, Katrin D., Andrade, Bruno B., Sher, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400546/
https://ncbi.nlm.nih.gov/pubmed/30787033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20181776
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