A major role for ferroptosis in Mycobacterium tuberculosis–induced cell death and tissue necrosis

Necrotic cell death during Mycobacterium tuberculosis (Mtb) infection is considered host detrimental since it facilitates mycobacterial spread. Ferroptosis is a type of regulated necrosis induced by accumulation of free iron and toxic lipid peroxides. We observed that Mtb-induced macrophage necrosis...

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Udgivet i:J Exp Med
Main Authors: Amaral, Eduardo P., Costa, Diego L., Namasivayam, Sivaranjani, Riteau, Nicolas, Kamenyeva, Olena, Mittereder, Lara, Mayer-Barber, Katrin D., Andrade, Bruno B., Sher, Alan
Format: Artigo
Sprog:Inglês
Udgivet: Rockefeller University Press 2019
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Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400546/
https://ncbi.nlm.nih.gov/pubmed/30787033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20181776
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