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Compound Shape Effects in Minor Groove Binding Affinity and Specificity for Mixed Sequence DNA
AT specific heterocyclic cations that bind in the DNA duplex minor groove have had major successes as cell and nuclear stains and as therapeutic agents which can effectively enter human cells. Expanding the DNA sequence recognition capability of the minor groove compounds could also expand their the...
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| Veröffentlicht in: | J Am Chem Soc |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6399738/ https://ncbi.nlm.nih.gov/pubmed/30353731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b08152 |
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