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Compound Shape Effects in Minor Groove Binding Affinity and Specificity for Mixed Sequence DNA

AT specific heterocyclic cations that bind in the DNA duplex minor groove have had major successes as cell and nuclear stains and as therapeutic agents which can effectively enter human cells. Expanding the DNA sequence recognition capability of the minor groove compounds could also expand their the...

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Bibliografiske detaljer
Udgivet i:J Am Chem Soc
Main Authors: Guo, Pu, Farahat, Abdelbasset A., Paul, Ananya, Harika, Narinder K., Boykin, David W., Wilson, W. David
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6399738/
https://ncbi.nlm.nih.gov/pubmed/30353731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b08152
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