Na(+)/Ca(2+) exchanger overexpression in smooth muscle augments cytosolic Ca(2+) in femoral arteries of living mice

Plasma membrane Na(+)/Ca(2+) exchanger-1 (NCX1) helps regulate the cytosolic Ca(2+) concentration ([Ca(2+)](CYT)) in arterial myocytes. NCX1 mediates both Ca(2+) entry and exit and tends to promote net Ca(2+) entry in partially constricted arteries. Mean blood pressure (telemetry) is elevated by ≈10...

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Vydáno v:Am J Physiol Heart Circ Physiol
Hlavní autoři: Zhang, Jin, Wang, Youhua, Chen, Ling, Wier, W. Gil, Blaustein, Mordecai P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2019
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6397384/
https://ncbi.nlm.nih.gov/pubmed/30461304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00185.2018
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