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Activation of L-type Ca(2+) channels by protein kinase C is reduced in smooth muscle-specific Na(+)/Ca(2+) exchanger knockout mice

L-type voltage-gated Ca(2+) channels (LVGCs) are functionally downregulated in arterial smooth muscle (SM) cells (ASMCs) of mice with SM-specific knockout of Na(+)/Ca(2+) exchanger type-1 (NCX1(SM−/−)) (32). Here, using activators and inhibitors of protein kinase C (PKC), we explore the regulation o...

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Detalhes bibliográficos
Main Authors: Ren, Chongyu, Zhang, Jin, Philipson, Kenneth D., Kotlikoff, Michael I., Blaustein, Mordecai P., Matteson, Donald R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867443/
https://ncbi.nlm.nih.gov/pubmed/20081108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00965.2009
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