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Excitation–Contraction Coupling in Na(+)–Ca(2+) Exchanger Knockout Mice: Reduced Transsarcolemmal Ca(2+) Flux

Cardiac-specific Na(+)–Ca(2+) exchanger (NCX) knockout (KO) mice surprisingly survive into adulthood without compensatory changes in protein expression levels. To determine how cardiac function is maintained in the absence of NCX, we investigated membrane currents, intracellular Ca(2+), and action p...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Pott, Christian, Philipson, Kenneth D., Goldhaber, Joshua I.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2005
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1790864/
https://ncbi.nlm.nih.gov/pubmed/16293789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/01.RES.0000196563.84231.21
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