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Excitation–Contraction Coupling in Na(+)–Ca(2+) Exchanger Knockout Mice: Reduced Transsarcolemmal Ca(2+) Flux

Cardiac-specific Na(+)–Ca(2+) exchanger (NCX) knockout (KO) mice surprisingly survive into adulthood without compensatory changes in protein expression levels. To determine how cardiac function is maintained in the absence of NCX, we investigated membrane currents, intracellular Ca(2+), and action p...

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Bibliografische gegevens
Hoofdauteurs: Pott, Christian, Philipson, Kenneth D., Goldhaber, Joshua I.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2005
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1790864/
https://ncbi.nlm.nih.gov/pubmed/16293789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/01.RES.0000196563.84231.21
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