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Excitation–Contraction Coupling in Na(+)–Ca(2+) Exchanger Knockout Mice: Reduced Transsarcolemmal Ca(2+) Flux
Cardiac-specific Na(+)–Ca(2+) exchanger (NCX) knockout (KO) mice surprisingly survive into adulthood without compensatory changes in protein expression levels. To determine how cardiac function is maintained in the absence of NCX, we investigated membrane currents, intracellular Ca(2+), and action p...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2005
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1790864/ https://ncbi.nlm.nih.gov/pubmed/16293789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/01.RES.0000196563.84231.21 |
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