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Na(+)/Ca(2+) exchanger overexpression in smooth muscle augments cytosolic Ca(2+) in femoral arteries of living mice
Plasma membrane Na(+)/Ca(2+) exchanger-1 (NCX1) helps regulate the cytosolic Ca(2+) concentration ([Ca(2+)](CYT)) in arterial myocytes. NCX1 mediates both Ca(2+) entry and exit and tends to promote net Ca(2+) entry in partially constricted arteries. Mean blood pressure (telemetry) is elevated by ≈10...
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| Publicado no: | Am J Physiol Heart Circ Physiol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6397384/ https://ncbi.nlm.nih.gov/pubmed/30461304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00185.2018 |
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