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NO-induced vasodilation correlates directly with BP in smooth muscle-Na/Ca exchanger-1-engineered mice: elevated BP does not attenuate endothelial function

Arterial smooth muscle Na(+)/Ca(2+) exchanger-1 (SM-NCX1) promotes vasoconstriction or vasodilation by mediating, respectively, Ca(2+) influx or efflux. In vivo, SM-NCX1 mediates net Ca(2+) influx to help maintain myogenic tone (MT) and neuronally activated constriction. SM-NCX1-TG (overexpressing t...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Wang, Youhua, Zhang, Jin, Wier, W.Gil, Chen, Ling, Blaustein, Mordecai P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7847073/
https://ncbi.nlm.nih.gov/pubmed/33124883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00487.2020
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