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NO-induced vasodilation correlates directly with BP in smooth muscle-Na/Ca exchanger-1-engineered mice: elevated BP does not attenuate endothelial function
Arterial smooth muscle Na(+)/Ca(2+) exchanger-1 (SM-NCX1) promotes vasoconstriction or vasodilation by mediating, respectively, Ca(2+) influx or efflux. In vivo, SM-NCX1 mediates net Ca(2+) influx to help maintain myogenic tone (MT) and neuronally activated constriction. SM-NCX1-TG (overexpressing t...
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| Publicado no: | Am J Physiol Heart Circ Physiol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7847073/ https://ncbi.nlm.nih.gov/pubmed/33124883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00487.2020 |
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