In vivo assessment of artery smooth muscle [Ca(2+)](i) and MLCK activation in FRET-based biosensor mice

The cellular mechanisms that control arterial diameter in vivo, particularly in hypertension, are uncertain. Here, we report a method that permits arterial intracellular Ca(2+) concentration ([Ca(2+)](i)), myosin light-chain kinase (MLCK) activation, and artery external diameter to be recorded simul...

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Bibliographic Details
Main Authors: Zhang, Jin, Chen, Ling, Raina, Hema, Blaustein, Mordecai P., Wier, W. Gil
Format: Artigo
Language:Inglês
Published: American Physiological Society 2010
Subjects:
Innovative Methodology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944472/
https://ncbi.nlm.nih.gov/pubmed/20622107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00359.2010
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