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In vivo assessment of artery smooth muscle [Ca(2+)](i) and MLCK activation in FRET-based biosensor mice
The cellular mechanisms that control arterial diameter in vivo, particularly in hypertension, are uncertain. Here, we report a method that permits arterial intracellular Ca(2+) concentration ([Ca(2+)](i)), myosin light-chain kinase (MLCK) activation, and artery external diameter to be recorded simul...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Physiological Society
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2944472/ https://ncbi.nlm.nih.gov/pubmed/20622107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00359.2010 |
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