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Knockout of Na(+)/Ca(2+) exchanger in smooth muscle attenuates vasoconstriction and L-type Ca(2+) channel current and lowers blood pressure
Mice with smooth muscle (SM)-specific knockout of Na(+)/Ca(2+) exchanger type-1 (NCX1(SM−/−)) and the NCX inhibitor, SEA0400, were used to study the physiological role of NCX1 in mouse mesenteric arteries. NCX1 protein expression was greatly reduced in arteries from NCX1(SM−/−) mice generated with C...
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| Hoofdauteurs: | , , , , , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Physiological Society
2010
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2867439/ https://ncbi.nlm.nih.gov/pubmed/20173044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00964.2009 |
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