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Interleukin-6 secretion is limited by self-signaling in endosomes

Cells producing cytokines often express the receptor for the same cytokine, which makes them prone to autocrine signaling. How cytokine release and signaling are regulated in the same cell is not understood. In this study, we demonstrate that signaling by exogenous and self-synthesized inflammatory...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Mol Cell Biol
Hauptverfasser: Verboogen, Daniëlle R J, Revelo, Natalia H, ter Beest, Martin, van den Bogaart, Geert
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6392102/
https://ncbi.nlm.nih.gov/pubmed/30016456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjy038
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