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Interleukin-6 secretion is limited by self-signaling in endosomes

Cells producing cytokines often express the receptor for the same cytokine, which makes them prone to autocrine signaling. How cytokine release and signaling are regulated in the same cell is not understood. In this study, we demonstrate that signaling by exogenous and self-synthesized inflammatory...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Mol Cell Biol
Egile Nagusiak: Verboogen, Daniëlle R J, Revelo, Natalia H, ter Beest, Martin, van den Bogaart, Geert
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6392102/
https://ncbi.nlm.nih.gov/pubmed/30016456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjy038
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