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Interleukin-6 secretion is limited by self-signaling in endosomes

Cells producing cytokines often express the receptor for the same cytokine, which makes them prone to autocrine signaling. How cytokine release and signaling are regulated in the same cell is not understood. In this study, we demonstrate that signaling by exogenous and self-synthesized inflammatory...

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Detalhes bibliográficos
Publicado no:J Mol Cell Biol
Main Authors: Verboogen, Daniëlle R J, Revelo, Natalia H, ter Beest, Martin, van den Bogaart, Geert
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6392102/
https://ncbi.nlm.nih.gov/pubmed/30016456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjy038
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