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Interleukin-6 secretion is limited by self-signaling in endosomes

Cells producing cytokines often express the receptor for the same cytokine, which makes them prone to autocrine signaling. How cytokine release and signaling are regulated in the same cell is not understood. In this study, we demonstrate that signaling by exogenous and self-synthesized inflammatory...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Mol Cell Biol
Prif Awduron: Verboogen, Daniëlle R J, Revelo, Natalia H, ter Beest, Martin, van den Bogaart, Geert
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6392102/
https://ncbi.nlm.nih.gov/pubmed/30016456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjy038
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