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Interleukin-6 secretion is limited by self-signaling in endosomes

Cells producing cytokines often express the receptor for the same cytokine, which makes them prone to autocrine signaling. How cytokine release and signaling are regulated in the same cell is not understood. In this study, we demonstrate that signaling by exogenous and self-synthesized inflammatory...

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Detalles Bibliográficos
Publicado en:J Mol Cell Biol
Autores principales: Verboogen, Daniëlle R J, Revelo, Natalia H, ter Beest, Martin, van den Bogaart, Geert
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6392102/
https://ncbi.nlm.nih.gov/pubmed/30016456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjy038
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