Lipid peroxidation causes endosomal antigen release for cross-presentation

Dendritic cells (DCs) present foreign antigen in major histocompatibility complex (MHC) class I molecules to cytotoxic T cells in a process called cross-presentation. An important step in this process is the release of antigen from the lumen of endosomes into the cytosol, but the mechanism of this s...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Dingjan, Ilse, Verboogen, Daniëlle RJ, Paardekooper, Laurent M, Revelo, Natalia H, Sittig, Simone P, Visser, Linda J, Mollard, Gabriele Fischer von, Henriet, Stefanie SV, Figdor, Carl G, ter Beest, Martin, van den Bogaart, Geert
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764948/
https://ncbi.nlm.nih.gov/pubmed/26907999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22064
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