Lipid peroxidation causes endosomal antigen release for cross-presentation

Dendritic cells (DCs) present foreign antigen in major histocompatibility complex (MHC) class I molecules to cytotoxic T cells in a process called cross-presentation. An important step in this process is the release of antigen from the lumen of endosomes into the cytosol, but the mechanism of this s...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Dingjan, Ilse, Verboogen, Daniëlle RJ, Paardekooper, Laurent M, Revelo, Natalia H, Sittig, Simone P, Visser, Linda J, Mollard, Gabriele Fischer von, Henriet, Stefanie SV, Figdor, Carl G, ter Beest, Martin, van den Bogaart, Geert
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764948/
https://ncbi.nlm.nih.gov/pubmed/26907999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22064
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