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VAMP8-mediated NOX2 recruitment to endosomes is necessary for antigen release
Cross-presentation of foreign antigen in major histocompatibility complex (MHC) class I by dendritic cells (DCs) requires activation of the NADPH-oxidase NOX2 complex. We recently showed that NOX2 is recruited to phagosomes by the SNARE protein VAMP8 where NOX2-produced reactive oxygen species (ROS)...
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| Publicado no: | Eur J Cell Biol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5641923/ https://ncbi.nlm.nih.gov/pubmed/28688576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejcb.2017.06.007 |
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