VAMP8-mediated NOX2 recruitment to endosomes is necessary for antigen release

Cross-presentation of foreign antigen in major histocompatibility complex (MHC) class I by dendritic cells (DCs) requires activation of the NADPH-oxidase NOX2 complex. We recently showed that NOX2 is recruited to phagosomes by the SNARE protein VAMP8 where NOX2-produced reactive oxygen species (ROS)...

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發表在:Eur J Cell Biol
Main Authors: Dingjan, Ilse, Paardekooper, Laurent M., Verboogen, Daniëlle R.J., von Mollard, Gabriele Fischer, ter Beest, Martin, van den Bogaart, Geert
格式: Artigo
語言:Inglês
出版: Elsevier 2017
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641923/
https://ncbi.nlm.nih.gov/pubmed/28688576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejcb.2017.06.007
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