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Characterization of Pyrin Dephosphorylation and Inflammasome Activation in Macrophages as Triggered by the Yersinia Effectors YopE and YopT

Pathogenic Yersinia species deliver Yop effector proteins through a type III secretion system into host cells. Among these effectors, YopE and YopT are Rho-modifying toxins, which function to modulate host cell physiology and evade immune responses. YopE is a GTPase-activating protein (GAP) while Yo...

詳細記述

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書誌詳細
出版年:Infect Immun
主要な著者: Medici, Natasha P., Rashid, Maheen, Bliska, James B.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6386549/
https://ncbi.nlm.nih.gov/pubmed/30602502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00822-18
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