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Yersinia pseudotuberculosis Virulence Determinants Invasin, YopE, and YopT Modulate RhoG Activity and Localization

The Yersinia pseudotuberculosis surface protein invasin binds to multiple β1 integrins with high affinity, leading to misregulation of Rac1 activity. Upon host cell binding, alteration of Rho GTPase activity results from the action of several Yersinia outer proteins (Yops) that are translocated into...

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Hlavní autoři: Mohammadi, Sina, Isberg, Ralph R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772528/
https://ncbi.nlm.nih.gov/pubmed/19720752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00850-09
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