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Gain-of-Function Analysis Reveals Important Virulence Roles for the Yersinia pestis Type III Secretion System Effectors YopJ, YopT, and YpkA

Virulence of Yersinia pestis in mammals requires the type III secretion system, which delivers seven effector proteins into the cytoplasm of host cells to undermine immune responses. All seven of these effectors are conserved across Y. pestis strains, but three, YopJ, YopT, and YpkA, are apparently...

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Bibliografische gegevens
Gepubliceerd in:Infect Immun
Hoofdauteurs: Palace, Samantha G., Proulx, Megan K., Szabady, Rose L., Goguen, Jon D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6105907/
https://ncbi.nlm.nih.gov/pubmed/29891548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00318-18
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