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Characterization of Pyrin Dephosphorylation and Inflammasome Activation in Macrophages as Triggered by the Yersinia Effectors YopE and YopT

Pathogenic Yersinia species deliver Yop effector proteins through a type III secretion system into host cells. Among these effectors, YopE and YopT are Rho-modifying toxins, which function to modulate host cell physiology and evade immune responses. YopE is a GTPase-activating protein (GAP) while Yo...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Medici, Natasha P., Rashid, Maheen, Bliska, James B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6386549/
https://ncbi.nlm.nih.gov/pubmed/30602502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00822-18
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