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The pyrin inflammasome and the Yersinia effector interaction
Pyrin is a cytosolic pattern-recognition receptor that normally functions as a guard to trigger capase-1 inflammasome assembly in response to bacterial toxins and effectors that inactivate RhoA. The MEFV gene encoding human pyrin is preferentially expressed in phagocytes. Key domains in pyrin includ...
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| Publicado no: | Immunol Rev |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7989412/ https://ncbi.nlm.nih.gov/pubmed/32721043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12907 |
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