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The pyrin inflammasome in host-microbe interactions
Pyrin is an inflammasome sensor in phagocytes that is activated in response to bacterial toxins and effectors that modify RhoA. Pathogen effector-triggered pyrin activation is analogous to an indirect guard mechanism in plants. Pyrin activation appears to be triggered when RhoA GTPases in a host cel...
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| Publicado no: | Curr Opin Microbiol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7247927/ https://ncbi.nlm.nih.gov/pubmed/32120337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mib.2020.01.005 |
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